Microcyn® clinical studies

  1. Hypochlorous Acid: An Ideal Wound Care Agent With Powerful Microbicidal, Antibiofilm, and Wound Healing Potency. WOUNDS 2014;26(12):342-350. Serhan Sakarya, MD; Necati Gunay, MS; Meltem Karakulak, MS; Barcin Ozturk, MD; Bulent Ertugrul, MD.
  2. Super-Oxidized Solution (Dermacyn Wound Care) as Adjuvant Treatment in the Postoperative Management of Complicated Diabetic Foot Osteomyelitis: Preliminary Experience in a Specialized Department. International Journal of Lower Extremity Wounds, pub. online 26 Feb., 2013. Javier Aragón-Sánchez, Jose L. Lázaro-Martínez, Yurena Quintana-Marrero, Irene Sanz-Corbalán, Maria J. Hernández-Herrero, Juan J. Cabrera-Galván
  3. Neutral super-oxidised solutions are effective in killing P. aeruginosa biofilms. Biofouling Vol. 25, No. 1, January 2009, 45–54. Karin Sauer, Eileen Thatcher, Robert Northey, Andres A. Gutierreza.
  4. An Open-label, Three-arm Pilot Study of the Safety andEfficacy of Topical Microcyn Rx Wound Care versus OralLevofloxacin versus Combined Therapy for Mild DiabeticFoot Infections. J Am Podiatr Med Assoc 101(6): 484-496, 201. Adam Landsman, DPM, PhD; Peter A. Blume, DPM; Douglas A. Jordan, Jr., DPM; Dean Vayser, DPM; Andres Gutierrez, MD, PhD.
  5. Diabetic Foot Management – Role of Superoxidised Solution. By Dr. Amar P. S. Suri MBBS, CPP (Podiatry) Beth Israel Hospital, Harvard, USA Diabetic Foot Fellowship- Temple Uni, USA Diabetic Footcare Center, New Delhi, India.
  6. Persistent Improvement of Diabetic Foot Ulcer Perfusion Results From Application of Superoxidized Water. Tcpo2 08.24.08.PPT. Cheryl M. Bongiovanni, PhD,RVT,CWS Lake District Hospital, Lakeview, OR.
  7. Why aren’t you using Microcyn Solution? Assistant Professor of Surgery, Harvard Medical School, Boston, MA Chief, Division of Podiatric Surgery, Cambridge Health Alliance, Cambridge, MA Research Director, California School of Podiatric Medicine at SMU, Oakland, CA.
  8. In vivo characterization of MicrocynTM effects on early phase of allergic reactions using a murine model of passive cutaneous anaphyaxis. April 9th, 2008. Elizabeth Sanchez- Miranda, Gonzalez, D., Gutierrez, AA., Gonzalez-Espinosa, C.
  9. Wound Healing in Chronic Lower Extremity Wounds Comparing Super-Oxidized Solution (SOS) vs. Saline. DFCON Poster 2008. Robert G. Frykberg, DPM, MPH; Arthur Tallis, DPM; Edward Tierney, DPM; Carl T. Hayden.
  10. Dermacyn® Effective in Treatment of Chronic Wounds with Extensive Bioburden while Reducing Local Pain Levels. POSTER – SAWC 07. Debra J. Peterson, CCRN, MSN, ACNP-BC; Karre Hermann, MSN, APNP-BC; Jeffrey A. Niezgoda MD, FACEP, FACHM.
  11. Dermacyn, A Novel Superoxidized Solution Facilitates Wound Healing Early Exp in Leg Wounds and Limb Salvage. POSTER – SAWC 06. David E. Allie, MD; Chris J Hebert, RT, R-CIS, Mitchell D Lirtzman, MD; Charles H Wyatt, MD; V Antoine Keller, MD; Adam A Allie, MS; Craig M Walker, MD.
  12. Sterilant for Human Wounds is Changing Patients’ Lives. Infection Control Today, November 2004 Vol. 8, No. 11. Fermin Martinez, MD.
  13. Efficacy and safety of neutral pH superoxidised solution in severe diabetic foot infections. Int Wound J 2007;4:353–362. Fermı´n R Martı´nez-De Jesu´s, Antonio Ramos-De la Medina, Jose´ Marı´a Remes-Troche, David G Armstrong, Stephanie C Wu, Jose Luis La´zaro Martı´nez, Juan V Beneit-Montesinos.
  14. Methicilin-resistent Staphylococcus aureus problem in health care. ABSTRACT – STUTTGART 05 – F-04-01-08. L.Veverkova, V.Jedlicka, M.Vesely, R.Tejkalova, S.Zabranska, I.Capov, M.Votava.
  15. Advanced Wound Care with Stable, Super-Oxidized Water. A look at how combination therapy can optimize wound healing. Supplement to January Wounds, 2006. Tom A. Wolvos, MD, FACS.
  16. Reducing Bacterial Infectious Complications from Burn Wounds. Supplement to January Wounds, 2006. A look at the use of Oculus Microcyn60 to treat wounds in Mexico. Ariel Miranda Altamirano, MD.
  17. A cytotoxic analysis of antiseptic medication on skin substitutes and autograft. British Journal of Dermatology 2007. Q. le Duc, M. Breetveld, E. Middelkoop, R.J. Scheper, M.M.W. Ulrich, S. Gibbs.
  18. The Science Behind Stable, Super-Oxidized Water. Exploring the various applications of super-oxidized solutions. Supplement to January Wounds, 2006. Andrés A. Gutiérrez, MD, PhD.
  19. Use of Dermacyn a new antiseptic agent for the local treatment of diabetic foot ulcers. ABSTRACT – STUTTGART 05. L.Dalla Paola, E.Brocco, A.Senesi, S.Ninkovic, M.Merico, D.De Vido.
  20. Treating Diabetic Foot Ulcers with Super-Oxidized Water. A look at advances in this pH-neutral, non-toxic treatment. Supplement to January Wounds, 2006. Luca Dalla Paola, MD.
  21. A Randomized Controlled Trial to Examine the Efficacy and Safety of a New Super-Oxididized Solution for the Management of Wide Postsurgical Lesions of the Diabetic Foot. The International Journal of Lower Extremity Wounds 9(1)10-15, 2010. A.Piaggesi, MD; C.Goretti, MD; S.Mazzurco, DPM; C.Tascini, MD; A.Leonildi, PhD, L.Rizzo, MD, A.Tedeschi, MD; G.Gemignani, MD; F.Menichetti, MD; S.Del Prato, MD, PhD.
  22. Activity of a pH Neutral Super-Oxidized Solution Against Bacteria Selected for Sodium Hypochlorite Resistance. J.Dardine, L.Diaz, C.Martinez, E.Thatcher.
  23. The Anti-Viral Efficacy of a New Super-Oxidized Solution. M.Taketa-Graham, A.A.Gutierrez, E.Thatcher.
  24. The Effectiveness of Neutral Ph,Super-oxidized Solution for the Treatment of Infected Diabetic Foot Wounds. Suri abstract DFCon 03.14.08.
  25. Clinical results about an antimicrobial solution (Dermacyn® Wound Care) in the treatment of infected chronic wounds. E.Ricci, S.Astolfi, R.Cassino.
  26. Clinical Outcomes of Wide Postsurgical Lesions in the Infected Diabetic Foot Managed With 2 Different Local Treatment Regimes Compared Using a Quasi-Experimental Study Design: A Preliminary Communication. Lower Extremity WOUNDS 6(1);2007 pp. 22-27. Chiara Goretti, Sabrina Mazzurco, Laura Ambrosini Nobili, Silvia Macchiarini, Anna Tedeschi, Francesca Palumbo, Alessia Scatena, Loredana Rizzo, Alberto Piaggesi.
  27. Efficacy and Safety of a Novel Super-Oxidized Solution in the Management of Wide Post-Chirurgical Lesion in the Infected Diabetic Foot. Chiara Goretti, Sabrina Mazzurco, Laura Ambrosini, Silvia Macchiarini, Anna Tedeschi, Francesca Palumbo, Alessia Scatena, Loredana Rizzo, Alberto Piaggesi.
  28. TREATING INFECTED DIABETIC WOUNDS WITH SUPEROXIDIZED WATER AS ANTI-SEPTIC AGENT : A PRELIMINARY EXPERIENCE. Accepted June 26, 2007. Syed Fazle Hadi, Tanwir Khaliq, Nighat Bilal, Imran Sikandar, Muhammad Saaiq, Muhammad Zubair, Sidra Aurangzeb.
  29. Treatment of Diabetic Foot Ulcer: An Overview Strategies for Clinical Approach. Current Diabetes Reviews, 2006, 2, 431-447. Luca Dalla Paola, Ezio Faglia.
  30. Comparative Efficacy and Tolerability of Oxum against Povidone Iodine Topical Application in the Post-caesarean Section Wound Management. Indian Medical Gazette, December 2007. Ashok Anand.
  31. Comparative Efficacy and Tolerability of Microcyn Superoxidized Solution (Oxum) against Povidone Iodine Application in Orodental Infections. Indian Medical Gazette, February 2008. Hemant Dhusia, Professor.
  32. Effects of pH Neutral, Super-Oxidized Solution On Human Dermal Fibroblasts In Vitro. González D, Pérez L, Guzmán B, Arias E, Bongiovanni C, Gutiérrez A A.
  33. Super-Oxidized Solution (SOS) Therapy for Diabetic Foot Ulcers. Fernando Uribe M.D. Prof.
  34. Super-oxidized solution inhibits IgE-antigen-induced degranulation and cytokine release in mast cells. International Immunopharmacology 7 (2007) 1013–1024. J. Medina-Tamayo, E. Sánchez-Miranda, H. Balleza-Tapia, X. Ambriz, M.E. Cid, D. González-Espinosa, A.A. Gutiérrez, C. González-Espinosa.
  35. Emerging Innovations In Treatment. Podiatry Today, September 11, 2006. Brian McCurdy, Senior Editor.
  36. MicrocynTM: a novel super-oxidized water with neutral pH and disinfectant activity. Received 30 August 2004; accepted 19 April 2005. C. Landa-Solis, D. Gonza´lez-Espinosa, B. Guzma´n-Soriano, M. Snyder, G. Reyes-Tera´n, K. Torres, A.A. Gutierrez.
  37. Clinical Outcomes of Wide Postsurgical Lesions in the Infected Diabetic Foot Managed With 2 Different Local Treatment Regimes Compared Using a Quasi-Experimental Study Design: A Preliminary Communication. March 6, 2007. Chiara Goretti, Sabrina Mazzurco, Laura Ambrosini
    Nobili, Silvia Macchiarini, Anna Tedeschi, Francesca Palumbo, Alessia Scatena, Loredana Rizzo, Alberto Piaggesi.
  38. Effects of pH-neutral, super-oxidised solution on human dermal fibroblasts in vitro. Int Wound J 2007;4:241–250. Diana Gonza´lez-Espinosa, Leafar Pe´rez-Romano, Beatriz Guzma´n-Soriano, Edmundo Arias, Cheryl M Bongiovanni, Andre´s A Gutie´rrez.
  39. Clinical Experience with a New, Stable, Super-Oxidized Water in Wound Treatment. WOUNDS, January 2006.
  40. Nonsurgical Management of Chronic Wounds in Patients With Diabetes. The Journal for Vascular Ultrasound 30(4):215–218, 2006. Cheryl M. Bongiovanni, PhD, RVT, CWS.
  41. Superoxidized Water Improves Wound Care Outcomes in Diabetic Patients. Diabetic Microvascular Complications Today, May/June 2006. Cheryl M. Bongiovanni, PHD.
  42. Super-Oxidized Solution (SOS) Therapy for Infected Diabetic Foot Ulcers. WOUNDS 2006;18(19):262-270. 2006Luca Dalla Paola, MD; Enrico Brocco, MD; Antonella Senesi, MD, PhD; Maurizio Merico, MD; Daniele De Vido, MD; Roberta Assaloni, MD; Roberto DaRos, MD.

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